MOTS-C Research Peptide, US-Made & Third-Party Tested
✓ US-made · third-party tested · free US shipping over $100
what is mots-c?
MOTS-c is a 16-amino-acid peptide encoded not by nuclear DNA but by a short open reading frame within the mitochondrial 12S rRNA gene. It belongs to the mitochondrial-derived peptide family, a group of small peptides that are of interest in research precisely because their genetic origin sits inside the organelle rather than the nucleus.
In cellular and pre-clinical models, MOTS-c is studied as a reference compound in mitochondrial-signaling research, including work on the AMPK pathway, folate–methionine one-carbon metabolism, and nuclear translocation of mitochondrially encoded peptides under metabolic stress. Verve manufactures MOTS-c in the United States, screens every batch by HPLC to a 99%+ purity standard, and publishes a batch-level certificate of analysis.
common research applications
MOTS-C is supplied strictly for laboratory research use only. Reported research contexts include:
- Mitochondrial-derived peptide and retrograde-signaling research
- AMPK pathway research models
- One-carbon (folate–methionine) metabolism studies
- Cellular energy-metabolism and substrate-utilization research
- Exercise-physiology and metabolic-stress research models
purity, testing & COA
Every batch of verve MOTS-C is synthesized and vial-filled in the United States and screened by an independent, accredited laboratory for identity, purity, and contaminants, with analysis by HPLC and, where appropriate, mass spectrometry. Products are manufactured to a 99%+ purity standard where stated, and an endotoxin-tested option is available for many compounds.
That lab report is the certificate of analysis. Match the batch code printed on your vial to the row in our COA library and you're reading the exact report for the exact vial in your hand. Every order includes a free downloadable COA, damage protection in transit, and full US tracking. Orders placed Monday–Friday ship by 2pm CT, free over $100.
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MOTS-Cweight & metabolicfrom $93browse all weight & metabolic →mots-c, frequently asked
What is MOTS-C?
MOTS-c is a 16-amino-acid peptide encoded by a short open reading frame in the mitochondrial genome. Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.
What is MOTS-C studied for in research?
It is used in mitochondrial-signaling research, including AMPK pathway activity, one-carbon metabolism, and retrograde signaling between mitochondria and the nucleus in in-vitro and pre-clinical models. Verve makes no health claims.
Why is MOTS-C called a mitochondrial-derived peptide?
Because its coding sequence lies within mitochondrial DNA rather than nuclear DNA. That unusual origin is a large part of why it is studied as a model compound in cellular-metabolism research.
How pure is Verve's MOTS-C, and is a COA included?
It is US-made, verified by HPLC to a 99%+ purity standard, and third-party tested, with a downloadable batch-level COA on every order matched to your vial's batch code.
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purity, proven.
US-made, third-party tested research peptides, every vial batch-traceable, every COA one click away.
verve products are sold for laboratory research and development purposes only and are not intended for human or veterinary use of any kind. statements on this site have not been evaluated by the FDA.