Epitalon vs MOTS-C
Epitalon and MOTS-C come from different research areas and are studied in largely separate models — researchers usually compare them when scoping a broader protocol.
✓ both US-made · third-party tested · batch COA on every order
at a glance
what each one is
Epitalon
Synthetic tetrapeptide
Epitalon is a synthetic tetrapeptide with the sequence alanyl-glutamyl-aspartyl-glycine (Ala-Glu-Asp-Gly), developed as a short synthetic analog of a peptide fraction isolated from the pineal gland. It is a small, water-soluble peptide and one of the most frequently cited reference compounds in pineal-peptide and cellular-aging research literature.
full Epitalon profile →MOTS-C
Mitochondrial-derived 16-amino-acid peptide
MOTS-c is a 16-amino-acid peptide encoded not by nuclear DNA but by a short open reading frame within the mitochondrial 12S rRNA gene. It belongs to the mitochondrial-derived peptide family, a group of small peptides that are of interest in research precisely because their genetic origin sits inside the organelle rather than the nucleus.
full MOTS-C profile →where the research differs
Both compounds are supplied strictly for laboratory research use only. Reported research contexts for each:
Epitalon
- Telomerase-expression research models
- Pineal-peptide and circadian-signaling research
- Chromatin and gene-regulation studies
- Cellular-senescence and replicative-aging research models
- Short-peptide stability and synthesis research
MOTS-C
- Mitochondrial-derived peptide and retrograde-signaling research
- AMPK pathway research models
- One-carbon (folate–methionine) metabolism studies
- Cellular energy-metabolism and substrate-utilization research
- Exercise-physiology and metabolic-stress research models
shop either compound
Any 2 different compounds take 20% off, any 3 take 30% — applied automatically in the cart, no code. Orders placed Monday–Friday ship by 2pm CT, free over $100.
build a stack with both →frequently asked
What is Epitalon?
Epitalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) based on a peptide fraction identified in the pineal gland. Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.
What is Epitalon studied for in research?
In in-vitro and pre-clinical research it is used as a reference compound in telomerase-expression, gene-regulation, cellular-senescence, and pineal-peptide signaling models. Verve makes no claims about use in humans or animals.
What is MOTS-C?
MOTS-c is a 16-amino-acid peptide encoded by a short open reading frame in the mitochondrial genome. Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.
What is MOTS-C studied for in research?
It is used in mitochondrial-signaling research, including AMPK pathway activity, one-carbon metabolism, and retrograde signaling between mitochondria and the nucleus in in-vitro and pre-clinical models. Verve makes no health claims.
related comparisons
verve products are sold for laboratory research and development purposes only and are not intended for human or veterinary use of any kind. statements on this site have not been evaluated by the FDA.