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small-molecule nnmt inhibitor · enzyme-inhibition research

5-Amino-1MQ Research Peptide, US-Made & Third-Party Tested

✓ US-made · third-party tested · free US shipping over $100

what is 5-amino-1mq?

5-Amino-1MQ is a small molecule rather than a peptide: a methylquinolinium compound that acts as a selective inhibitor of nicotinamide N-methyltransferase (NNMT). It is cell-permeable and carries a permanent positive charge on its quaternary nitrogen, a structural feature that shapes how it distributes in cellular assays and why it is used as a tool compound in enzyme-inhibition research.

NNMT sits at a junction between nicotinamide handling and the methyl-donor pool, so 5-Amino-1MQ is studied in vitro and in pre-clinical models as a probe of NNMT enzyme kinetics, NAD+ salvage-pathway flux, and S-adenosylmethionine methylation balance. Verve manufactures 5-Amino-1MQ in the United States, screens every batch to a high-purity research standard, and publishes a batch-level certificate of analysis.

common research applications

5-Amino-1MQ is supplied strictly for laboratory research use only. Reported research contexts include:

  • NNMT enzyme-inhibition and kinetics research
  • NAD+ salvage-pathway and nicotinamide-metabolism studies
  • S-adenosylmethionine and methyl-donor balance research
  • Adipocyte and cellular energy-metabolism research models
  • Small-molecule structure–activity and selectivity studies

purity, testing & COA

Every batch of verve 5-Amino-1MQ is synthesized and vial-filled in the United States and screened by an independent, accredited laboratory for identity, purity, and contaminants, with analysis by HPLC and, where appropriate, mass spectrometry. Products are manufactured to a 99%+ purity standard where stated, and an endotoxin-tested option is available for many compounds.

That lab report is the certificate of analysis. Match the batch code printed on your vial to the row in our COA library and you're reading the exact report for the exact vial in your hand. Every order includes a free downloadable COA, damage protection in transit, and full US tracking. Orders placed Monday–Friday ship by 2pm CT, free over $100.

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5-amino-1mq, frequently asked

What is 5-Amino-1MQ?

5-Amino-1MQ is a small molecule, not a peptide — a methylquinolinium compound that selectively inhibits the enzyme nicotinamide N-methyltransferase (NNMT). Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.

Is 5-Amino-1MQ a peptide?

No. It is a small-molecule enzyme inhibitor with no amino-acid backbone, which is why it is handled and stored differently from the peptides in the catalog. It is supplied strictly for laboratory research.

What is 5-Amino-1MQ studied for in research?

It is used as a tool compound in NNMT enzyme-inhibition research, NAD+ salvage-pathway studies, and methyl-donor metabolism models in vitro and pre-clinically. Verve makes no claims about use in humans or animals.

How pure is Verve's 5-Amino-1MQ, and is a COA included?

It is US-made, prepared and screened to a high-purity research standard, and third-party tested, with a downloadable batch-level certificate of analysis on every order.

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purity, proven.

US-made, third-party tested research peptides, every vial batch-traceable, every COA one click away.

verve products are sold for laboratory research and development purposes only and are not intended for human or veterinary use of any kind. statements on this site have not been evaluated by the FDA.