AOD-9604 vs MOTS-C
AOD-9604 and MOTS-C are both studied in weight research, but they are different classes of compound with different reported research applications.
✓ both US-made · third-party tested · batch COA on every order
at a glance
what each one is
AOD-9604
Modified human growth hormone fragment
AOD-9604 is a synthetic peptide corresponding to the C-terminal 176–191 fragment of human growth hormone, modified by the addition of a tyrosine residue at the N-terminus to improve stability. Unlike the full-length hormone, the fragment lacks the regions associated with growth-hormone receptor binding, which is what makes it useful as a dissociated structural probe in research.
full AOD-9604 profile →MOTS-C
Mitochondrial-derived 16-amino-acid peptide
MOTS-c is a 16-amino-acid peptide encoded not by nuclear DNA but by a short open reading frame within the mitochondrial 12S rRNA gene. It belongs to the mitochondrial-derived peptide family, a group of small peptides that are of interest in research precisely because their genetic origin sits inside the organelle rather than the nucleus.
full MOTS-C profile →where the research differs
Both compounds are supplied strictly for laboratory research use only. Reported research contexts for each:
AOD-9604
- Lipid-metabolism and adipocyte-signaling research models
- Growth-hormone fragment structure–activity research
- Lipolytic and lipogenic enzyme pathway studies
- Comparative studies against full-length growth hormone
- Body-composition research endpoints in pre-clinical models
MOTS-C
- Mitochondrial-derived peptide and retrograde-signaling research
- AMPK pathway research models
- One-carbon (folate–methionine) metabolism studies
- Cellular energy-metabolism and substrate-utilization research
- Exercise-physiology and metabolic-stress research models
shop either compound
Any 2 different compounds take 20% off, any 3 take 30% — applied automatically in the cart, no code. Orders placed Monday–Friday ship by 2pm CT, free over $100.
build a stack with both →frequently asked
What is AOD-9604?
AOD-9604 is a synthetic peptide based on the 176–191 C-terminal fragment of human growth hormone, with an added N-terminal tyrosine. Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.
What is AOD-9604 studied for in research?
It is used as a reference compound in lipid-metabolism, adipocyte-signaling, and enzyme-pathway research, and in structure–activity studies comparing fragments to full-length growth hormone. Verve makes no claims about use in humans or animals.
What is MOTS-C?
MOTS-c is a 16-amino-acid peptide encoded by a short open reading frame in the mitochondrial genome. Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.
What is MOTS-C studied for in research?
It is used in mitochondrial-signaling research, including AMPK pathway activity, one-carbon metabolism, and retrograde signaling between mitochondria and the nucleus in in-vitro and pre-clinical models. Verve makes no health claims.
related comparisons
verve products are sold for laboratory research and development purposes only and are not intended for human or veterinary use of any kind. statements on this site have not been evaluated by the FDA.