IGF-1 LR3 vs WOLVERINE
IGF-1 LR3 and WOLVERINE come from different research areas and are studied in largely separate models — researchers usually compare them when scoping a broader protocol.
✓ both US-made · third-party tested · batch COA on every order
at a glance
what each one is
IGF-1 LR3
Recombinant IGF-1 analog polypeptide
IGF-1 LR3 is Long R3 insulin-like growth factor 1, a recombinant analog of human IGF-1 carrying an arginine substitution at position 3 and a 13-residue N-terminal extension. Those two modifications are what define it: they substantially reduce its affinity for the insulin-like growth factor binding proteins (IGFBPs) that sequester native IGF-1 in culture systems.
full IGF-1 LR3 profile →WOLVERINE
Co-formulated two-peptide research blend
WOLVERINE is a co-formulated research blend that combines two of the most frequently cited reference peptides in tissue-repair literature, BPC-157 / TB-500, in a single vial. BPC-157 is a synthetic pentadecapeptide derived from a partial sequence identified in human gastric juice; TB-500 is a synthetic 43-amino-acid peptide corresponding to an active fragment of thymosin beta-4, a naturally-occurring actin-binding protein.
full WOLVERINE profile →where the research differs
Both compounds are supplied strictly for laboratory research use only. Reported research contexts for each:
IGF-1 LR3
- IGF-1 receptor binding and signal-transduction research
- PI3K/Akt and MAPK pathway research in cellular models
- Cell-culture media supplementation for proliferation research
- IGFBP interaction and free-ligand availability studies
- Comparative analog research against native IGF-1
WOLVERINE
- Multi-compound tissue-repair research models
- Cell-migration and wound-healing research
- Angiogenesis and vascular-signaling research
- Actin-regulation and cytoskeletal research
- Comparative research on blended versus single-peptide preparations
shop either compound
Any 2 different compounds take 20% off, any 3 take 30% — applied automatically in the cart, no code. Orders placed Monday–Friday ship by 2pm CT, free over $100.
build a stack with both →frequently asked
What is IGF-1 LR3?
IGF-1 LR3 is Long R3 insulin-like growth factor 1, a recombinant analog of human IGF-1 with an arginine substitution at position 3 and an N-terminal extension. Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.
How does IGF-1 LR3 differ from native IGF-1?
Its structural modifications reduce affinity for IGF binding proteins, so more of the ligand remains unbound in culture systems. Researchers use that property to control free-ligand availability in in-vitro models.
What is WOLVERINE?
WOLVERINE is a co-formulated research blend of two well-characterized reference peptides, BPC-157 / TB-500, supplied in one vial. Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.
What is the BPC-157 / TB-500 blend studied for in research?
It is used in multi-compound cellular models covering tissue repair, cell migration, angiogenesis, and actin regulation, where both peptides are studied together. Verve makes no health claims.
related comparisons
verve products are sold for laboratory research and development purposes only and are not intended for human or veterinary use of any kind. statements on this site have not been evaluated by the FDA.