IGF-1 LR3 Research Peptide, US-Made & Third-Party Tested
✓ US-made · third-party tested · free US shipping over $100
what is igf-1 lr3?
IGF-1 LR3 is Long R3 insulin-like growth factor 1, a recombinant analog of human IGF-1 carrying an arginine substitution at position 3 and a 13-residue N-terminal extension. Those two modifications are what define it: they substantially reduce its affinity for the insulin-like growth factor binding proteins (IGFBPs) that sequester native IGF-1 in culture systems.
That reduced binding-protein affinity is the reason IGF-1 LR3 is widely used as a supplement in cell-culture media and as a reference ligand in IGF-1-receptor signaling research, where free-ligand availability would otherwise be difficult to control. Verve manufactures IGF-1 LR3 in the United States, tests every batch to a high-purity research standard, and publishes a batch-level certificate of analysis.
common research applications
IGF-1 LR3 is supplied strictly for laboratory research use only. Reported research contexts include:
- IGF-1 receptor binding and signal-transduction research
- PI3K/Akt and MAPK pathway research in cellular models
- Cell-culture media supplementation for proliferation research
- IGFBP interaction and free-ligand availability studies
- Comparative analog research against native IGF-1
purity, testing & COA
Every batch of verve IGF-1 LR3 is synthesized and vial-filled in the United States and screened by an independent, accredited laboratory for identity, purity, and contaminants, with analysis by HPLC and, where appropriate, mass spectrometry. Products are manufactured to a 99%+ purity standard where stated, and an endotoxin-tested option is available for many compounds.
That lab report is the certificate of analysis. Match the batch code printed on your vial to the row in our COA library and you're reading the exact report for the exact vial in your hand. Every order includes a free downloadable COA, damage protection in transit, and full US tracking. Orders placed Monday–Friday ship by 2pm CT, free over $100.
igf-1 lr3, frequently asked
What is IGF-1 LR3?
IGF-1 LR3 is Long R3 insulin-like growth factor 1, a recombinant analog of human IGF-1 with an arginine substitution at position 3 and an N-terminal extension. Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.
How does IGF-1 LR3 differ from native IGF-1?
Its structural modifications reduce affinity for IGF binding proteins, so more of the ligand remains unbound in culture systems. Researchers use that property to control free-ligand availability in in-vitro models.
What is IGF-1 LR3 studied for in research?
It is used as a reference ligand in IGF-1-receptor binding and downstream signal-transduction research, and as a cell-culture supplement in proliferation studies. Verve makes no claims about effects in humans or animals.
How pure is Verve's IGF-1 LR3, and is a COA included?
It is US-made, prepared and tested to a high-purity research standard, and shipped with a downloadable batch-level certificate of analysis matched to your vial's batch code.
research areas igf-1 lr3 appears in
compare igf-1 lr3
all comparisons →related research compounds
purity, proven.
US-made, third-party tested research peptides, every vial batch-traceable, every COA one click away.
verve products are sold for laboratory research and development purposes only and are not intended for human or veterinary use of any kind. statements on this site have not been evaluated by the FDA.