IGF-1 LR3 vs Thymosin Alpha-1
IGF-1 LR3 and Thymosin Alpha-1 are both studied in longevity research, but they are different classes of compound with different reported research applications.
✓ both US-made · third-party tested · batch COA on every order
at a glance
what each one is
IGF-1 LR3
Recombinant IGF-1 analog polypeptide
IGF-1 LR3 is Long R3 insulin-like growth factor 1, a recombinant analog of human IGF-1 carrying an arginine substitution at position 3 and a 13-residue N-terminal extension. Those two modifications are what define it: they substantially reduce its affinity for the insulin-like growth factor binding proteins (IGFBPs) that sequester native IGF-1 in culture systems.
full IGF-1 LR3 profile →Thymosin Alpha-1
Synthetic 28-amino-acid thymic peptide
Thymosin Alpha-1 is a 28-amino-acid peptide corresponding to a sequence originally characterized in thymic tissue extracts, where it was identified as part of the prothymosin alpha precursor. Verve supplies it as a high-purity synthetic research compound for the laboratory study of peptide-mediated immunological signaling.
full Thymosin Alpha-1 profile →where the research differs
Both compounds are supplied strictly for laboratory research use only. Reported research contexts for each:
IGF-1 LR3
- IGF-1 receptor binding and signal-transduction research
- PI3K/Akt and MAPK pathway research in cellular models
- Cell-culture media supplementation for proliferation research
- IGFBP interaction and free-ligand availability studies
- Comparative analog research against native IGF-1
Thymosin Alpha-1
- T-cell differentiation and maturation research models
- Toll-like receptor signaling research
- Cytokine-expression profiling in cell culture
- Thymic-peptide and immunological-signaling research
- Peptide structure–activity and stability research
shop either compound
Any 2 different compounds take 20% off, any 3 take 30% — applied automatically in the cart, no code. Orders placed Monday–Friday ship by 2pm CT, free over $100.
build a stack with both →frequently asked
What is IGF-1 LR3?
IGF-1 LR3 is Long R3 insulin-like growth factor 1, a recombinant analog of human IGF-1 with an arginine substitution at position 3 and an N-terminal extension. Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.
How does IGF-1 LR3 differ from native IGF-1?
Its structural modifications reduce affinity for IGF binding proteins, so more of the ligand remains unbound in culture systems. Researchers use that property to control free-ligand availability in in-vitro models.
What is Thymosin Alpha-1?
Thymosin Alpha-1 is a synthetic 28-amino-acid peptide based on a sequence characterized in thymic tissue. Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.
What is Thymosin Alpha-1 studied for in research?
It is used as a reference compound in immunological-signaling research, including T-cell differentiation models, Toll-like receptor pathway studies, and cytokine-expression profiling in cultured cells. Verve makes no health claims.
related comparisons
verve products are sold for laboratory research and development purposes only and are not intended for human or veterinary use of any kind. statements on this site have not been evaluated by the FDA.