IGF-1 LR3 vs TB-500
IGF-1 LR3 and TB-500 come from different research areas and are studied in largely separate models — researchers usually compare them when scoping a broader protocol.
✓ both US-made · third-party tested · batch COA on every order
at a glance
what each one is
IGF-1 LR3
Recombinant IGF-1 analog polypeptide
IGF-1 LR3 is Long R3 insulin-like growth factor 1, a recombinant analog of human IGF-1 carrying an arginine substitution at position 3 and a 13-residue N-terminal extension. Those two modifications are what define it: they substantially reduce its affinity for the insulin-like growth factor binding proteins (IGFBPs) that sequester native IGF-1 in culture systems.
full IGF-1 LR3 profile →TB-500
Thymosin β4 fragment · tissue-repair research
TB-500 is a synthetic 43-amino-acid peptide corresponding to an active fragment of thymosin beta-4, a naturally-occurring actin-binding protein. Verve supplies it as a high-purity research compound for tissue-repair and cellular research.
full TB-500 profile →where the research differs
Both compounds are supplied strictly for laboratory research use only. Reported research contexts for each:
IGF-1 LR3
- IGF-1 receptor binding and signal-transduction research
- PI3K/Akt and MAPK pathway research in cellular models
- Cell-culture media supplementation for proliferation research
- IGFBP interaction and free-ligand availability studies
- Comparative analog research against native IGF-1
TB-500
- Cell-migration research models
- Actin-regulation and cytoskeletal research
- Angiogenesis research
- Tissue-repair research models
shop either compound
Any 2 different compounds take 20% off, any 3 take 30% — applied automatically in the cart, no code. Orders placed Monday–Friday ship by 2pm CT, free over $100.
build a stack with both →frequently asked
What is IGF-1 LR3?
IGF-1 LR3 is Long R3 insulin-like growth factor 1, a recombinant analog of human IGF-1 with an arginine substitution at position 3 and an N-terminal extension. Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.
How does IGF-1 LR3 differ from native IGF-1?
Its structural modifications reduce affinity for IGF binding proteins, so more of the ligand remains unbound in culture systems. Researchers use that property to control free-ligand availability in in-vitro models.
What is TB-500?
TB-500 is a synthetic 43-amino-acid peptide based on an active fragment of thymosin beta-4. Verve supplies it as a research compound for laboratory use only.
What is TB-500 studied for in research?
It is used in cell-migration, actin-regulation, angiogenesis, and tissue-repair research models. It is not for human or veterinary use.
related comparisons
verve products are sold for laboratory research and development purposes only and are not intended for human or veterinary use of any kind. statements on this site have not been evaluated by the FDA.