IGF-1 LR3 vs NAD+
IGF-1 LR3 and NAD+ are both studied in longevity research, but they are different classes of compound with different reported research applications.
✓ both US-made · third-party tested · batch COA on every order
at a glance
what each one is
IGF-1 LR3
Recombinant IGF-1 analog polypeptide
IGF-1 LR3 is Long R3 insulin-like growth factor 1, a recombinant analog of human IGF-1 carrying an arginine substitution at position 3 and a 13-residue N-terminal extension. Those two modifications are what define it: they substantially reduce its affinity for the insulin-like growth factor binding proteins (IGFBPs) that sequester native IGF-1 in culture systems.
full IGF-1 LR3 profile →NAD+
Nicotinamide adenine dinucleotide · cellular-metabolism research
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme present in every living cell and central to redox reactions and cellular energy metabolism. Verve's NAD+ is a high-purity research preparation supplied for the laboratory study of cellular energetics and redox biology.
full NAD+ profile →where the research differs
Both compounds are supplied strictly for laboratory research use only. Reported research contexts for each:
IGF-1 LR3
- IGF-1 receptor binding and signal-transduction research
- PI3K/Akt and MAPK pathway research in cellular models
- Cell-culture media supplementation for proliferation research
- IGFBP interaction and free-ligand availability studies
- Comparative analog research against native IGF-1
NAD+
- Cellular energy-metabolism research
- Sirtuin and PARP enzyme research
- Mitochondrial-function research models
- Redox-biology (NAD+/NADH ratio) research
- Longevity and cellular-aging research models
shop either compound
Any 2 different compounds take 20% off, any 3 take 30% — applied automatically in the cart, no code. Orders placed Monday–Friday ship by 2pm CT, free over $100.
build a stack with both →frequently asked
What is IGF-1 LR3?
IGF-1 LR3 is Long R3 insulin-like growth factor 1, a recombinant analog of human IGF-1 with an arginine substitution at position 3 and an N-terminal extension. Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.
How does IGF-1 LR3 differ from native IGF-1?
Its structural modifications reduce affinity for IGF binding proteins, so more of the ligand remains unbound in culture systems. Researchers use that property to control free-ligand availability in in-vitro models.
What is NAD+?
NAD+ is nicotinamide adenine dinucleotide, a coenzyme central to redox reactions and energy metabolism in cells. Verve supplies a high-purity research preparation for laboratory use only.
What is NAD+ studied for in research?
It is used in research on cellular energy metabolism, sirtuin and PARP enzyme activity, mitochondrial function, and DNA-repair pathways. It is not for human or veterinary use.
related comparisons
verve products are sold for laboratory research and development purposes only and are not intended for human or veterinary use of any kind. statements on this site have not been evaluated by the FDA.