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side-by-side research comparison

Melanotan I vs SNAP-8

Melanotan I and SNAP-8 are both studied in skin research, but they are different classes of compound with different reported research applications.

✓ both US-made · third-party tested · batch COA on every order

at a glance

Melanotan ISNAP-8
compound classSynthetic linear tridecapeptideSynthetic acetylated octapeptide
research areaskin & glowskin & glow
purity standard99%+ by HPLC99%+ by HPLC
manufacturedUnited StatesUnited States
batch COApublished per lotpublished per lot
price from$79.99$43.49
availabilityout of stockout of stock

what each one is

Melanotan I

Synthetic linear tridecapeptide

Melanotan I, also known as afamelanotide, is a synthetic linear tridecapeptide and a structural analog of alpha-melanocyte-stimulating hormone (alpha-MSH), the endogenous ligand of the melanocortin receptor family. Substitutions to the native alpha-MSH sequence give the analog greater resistance to enzymatic degradation, which is why it is frequently selected as a stable reference ligand in melanocortin-pathway research.

full Melanotan I profile →

SNAP-8

Synthetic acetylated octapeptide

SNAP-8 is a synthetic acetylated octapeptide, an elongated analog of acetyl hexapeptide-3 (Argireline) extended by two additional residues. Its sequence is modeled on the N-terminal region of SNAP-25, one of the proteins that assembles the SNARE complex, which makes it a convenient synthetic tool for studying that assembly in vitro.

full SNAP-8 profile →

where the research differs

Both compounds are supplied strictly for laboratory research use only. Reported research contexts for each:

Melanotan I

  • Melanocortin-1 receptor (MC1R) binding and selectivity research
  • Melanogenesis research in cultured melanocyte models
  • cAMP second-messenger signaling research
  • Comparative alpha-MSH analog and receptor-agonist studies
  • Peptide-stability and enzymatic-degradation research

SNAP-8

  • SNARE-complex assembly research
  • Neurotransmitter-vesicle docking and fusion research models
  • SNAP-25 competitive-peptide studies
  • Dermal cell-culture and fibroblast research models
  • Comparative octapeptide and hexapeptide analog research

shop either compound

Melanotan Icurrently out of stock
SNAP-8currently out of stock

Any 2 different compounds take 20% off, any 3 take 30% — applied automatically in the cart, no code. Orders placed Monday–Friday ship by 2pm CT, free over $100.

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frequently asked

What is Melanotan I?

Melanotan I (afamelanotide) is a synthetic tridecapeptide analog of alpha-melanocyte-stimulating hormone. Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.

What is Melanotan I studied for in research?

It is used as a reference MC1R agonist in melanocortin receptor-binding, cAMP signaling, and melanogenesis research models in cultured cells. Verve makes no claims about use in humans or animals.

What is SNAP-8?

SNAP-8 is a synthetic acetylated octapeptide, an elongated analog of acetyl hexapeptide-3 (Argireline), based on a sequence from the SNAP-25 protein. Verve supplies it as a research compound for laboratory use only.

What is SNAP-8 studied for in research?

It is used as a peptide model in SNARE-complex and neurotransmitter-vesicle research, and as a reference compound in dermal cell-culture studies. It is not for human or veterinary use.

related comparisons

verve products are sold for laboratory research and development purposes only and are not intended for human or veterinary use of any kind. statements on this site have not been evaluated by the FDA.