Melanotan I vs PT-141
Melanotan I and PT-141 are both studied in skin research, but they are different classes of compound with different reported research applications.
✓ both US-made · third-party tested · batch COA on every order
at a glance
what each one is
Melanotan I
Synthetic linear tridecapeptide
Melanotan I, also known as afamelanotide, is a synthetic linear tridecapeptide and a structural analog of alpha-melanocyte-stimulating hormone (alpha-MSH), the endogenous ligand of the melanocortin receptor family. Substitutions to the native alpha-MSH sequence give the analog greater resistance to enzymatic degradation, which is why it is frequently selected as a stable reference ligand in melanocortin-pathway research.
full Melanotan I profile →PT-141
Synthetic cyclic heptapeptide melanocortin agonist
PT-141, also known as bremelanotide, is a synthetic cyclic heptapeptide analog of the melanocortin family, structurally related to alpha-melanocyte-stimulating hormone and to the earlier research analog Melanotan II. Verve supplies it as a high-purity research compound for laboratory melanocortin-receptor research.
full PT-141 profile →where the research differs
Both compounds are supplied strictly for laboratory research use only. Reported research contexts for each:
Melanotan I
- Melanocortin-1 receptor (MC1R) binding and selectivity research
- Melanogenesis research in cultured melanocyte models
- cAMP second-messenger signaling research
- Comparative alpha-MSH analog and receptor-agonist studies
- Peptide-stability and enzymatic-degradation research
PT-141
- Melanocortin-receptor (MC1R/MC3R/MC4R) binding research
- cAMP and G-protein-coupled receptor signaling assays
- Receptor-selectivity and structure–activity profiling
- MC1R and melanogenesis research models in cell culture
- Cyclic-peptide stability and conformation research
shop either compound
Any 2 different compounds take 20% off, any 3 take 30% — applied automatically in the cart, no code. Orders placed Monday–Friday ship by 2pm CT, free over $100.
build a stack with both →frequently asked
What is Melanotan I?
Melanotan I (afamelanotide) is a synthetic tridecapeptide analog of alpha-melanocyte-stimulating hormone. Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.
What is Melanotan I studied for in research?
It is used as a reference MC1R agonist in melanocortin receptor-binding, cAMP signaling, and melanogenesis research models in cultured cells. Verve makes no claims about use in humans or animals.
What is PT-141?
PT-141 (bremelanotide) is a synthetic cyclic heptapeptide melanocortin analog structurally related to alpha-MSH. Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.
What is PT-141 studied for in research?
It is used as a reference agonist in melanocortin-receptor research, including MC1R, MC3R, and MC4R binding studies, cAMP signaling assays, and receptor-selectivity profiling. Verve makes no health claims.
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verve products are sold for laboratory research and development purposes only and are not intended for human or veterinary use of any kind. statements on this site have not been evaluated by the FDA.