CJC-1295 / Ipamorelin vs PT-141
CJC-1295 / Ipamorelin and PT-141 come from different research areas and are studied in largely separate models — researchers usually compare them when scoping a broader protocol.
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at a glance
what each one is
CJC-1295 / Ipamorelin
Co-formulated GHRH-analog and secretagogue blend
CJC-1295 / Ipamorelin is a co-formulated research blend of two peptides that act at separate receptors. CJC-1295 without DAC, also referred to as Mod GRF 1-29, is a modified 29-amino-acid analog of growth-hormone-releasing hormone characterized as a GHRH-receptor agonist. Ipamorelin is a synthetic pentapeptide characterized as a selective agonist at the growth-hormone secretagogue receptor, GHS-R1a.
full CJC-1295 / Ipamorelin profile →PT-141
Synthetic cyclic heptapeptide melanocortin agonist
PT-141, also known as bremelanotide, is a synthetic cyclic heptapeptide analog of the melanocortin family, structurally related to alpha-melanocyte-stimulating hormone and to the earlier research analog Melanotan II. Verve supplies it as a high-purity research compound for laboratory melanocortin-receptor research.
full PT-141 profile →where the research differs
Both compounds are supplied strictly for laboratory research use only. Reported research contexts for each:
CJC-1295 / Ipamorelin
- Dual-pathway GHRH-receptor and GHS-R1a signaling research
- Receptor cross-talk and signal-transduction research models
- Comparative agonist research versus single-component preparations
- Endocrine-signaling research in cellular and pre-clinical models
- Peptide stability and analog structure–activity research
PT-141
- Melanocortin-receptor (MC1R/MC3R/MC4R) binding research
- cAMP and G-protein-coupled receptor signaling assays
- Receptor-selectivity and structure–activity profiling
- MC1R and melanogenesis research models in cell culture
- Cyclic-peptide stability and conformation research
shop either compound
Any 2 different compounds take 20% off, any 3 take 30% — applied automatically in the cart, no code. Orders placed Monday–Friday ship by 2pm CT, free over $100.
build a stack with both →frequently asked
What is CJC-1295 / Ipamorelin?
It is a co-formulated research blend of CJC-1295 without DAC (also called Mod GRF 1-29), a GHRH analog, and ipamorelin, a selective GHS-R1a agonist. Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.
What is the difference between CJC-1295 with and without DAC?
The DAC (drug affinity complex) modification is a chemical addition studied for its effect on the analog's circulating half-life in pre-clinical models. The no-DAC form, Mod GRF 1-29, lacks that modification and is the component used in this blend.
What is PT-141?
PT-141 (bremelanotide) is a synthetic cyclic heptapeptide melanocortin analog structurally related to alpha-MSH. Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.
What is PT-141 studied for in research?
It is used as a reference agonist in melanocortin-receptor research, including MC1R, MC3R, and MC4R binding studies, cAMP signaling assays, and receptor-selectivity profiling. Verve makes no health claims.
related comparisons
verve products are sold for laboratory research and development purposes only and are not intended for human or veterinary use of any kind. statements on this site have not been evaluated by the FDA.