CJC-1295 / Ipamorelin vs Ipamorelin
CJC-1295 / Ipamorelin and Ipamorelin are both studied in longevity research, but they are different classes of compound with different reported research applications.
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at a glance
what each one is
CJC-1295 / Ipamorelin
Co-formulated GHRH-analog and secretagogue blend
CJC-1295 / Ipamorelin is a co-formulated research blend of two peptides that act at separate receptors. CJC-1295 without DAC, also referred to as Mod GRF 1-29, is a modified 29-amino-acid analog of growth-hormone-releasing hormone characterized as a GHRH-receptor agonist. Ipamorelin is a synthetic pentapeptide characterized as a selective agonist at the growth-hormone secretagogue receptor, GHS-R1a.
full CJC-1295 / Ipamorelin profile →Ipamorelin
Synthetic pentapeptide secretagogue
Ipamorelin is a synthetic pentapeptide and a selective growth-hormone secretagogue, meaning it is characterized in the literature as an agonist at the growth-hormone secretagogue receptor (GHS-R1a), the same receptor targeted by the endogenous ligand ghrelin. Its selectivity profile is the reason it is so frequently chosen as a reference agonist in receptor-signaling work.
full Ipamorelin profile →where the research differs
Both compounds are supplied strictly for laboratory research use only. Reported research contexts for each:
CJC-1295 / Ipamorelin
- Dual-pathway GHRH-receptor and GHS-R1a signaling research
- Receptor cross-talk and signal-transduction research models
- Comparative agonist research versus single-component preparations
- Endocrine-signaling research in cellular and pre-clinical models
- Peptide stability and analog structure–activity research
Ipamorelin
- GHS-R1a (ghrelin receptor) binding and agonist research
- Secretagogue-pathway signal-transduction research
- Comparative receptor-selectivity studies against non-selective secretagogues
- Endocrine-signaling research models
- Peptide stability and structure–activity research
shop either compound
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build a stack with both →frequently asked
What is CJC-1295 / Ipamorelin?
It is a co-formulated research blend of CJC-1295 without DAC (also called Mod GRF 1-29), a GHRH analog, and ipamorelin, a selective GHS-R1a agonist. Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.
What is the difference between CJC-1295 with and without DAC?
The DAC (drug affinity complex) modification is a chemical addition studied for its effect on the analog's circulating half-life in pre-clinical models. The no-DAC form, Mod GRF 1-29, lacks that modification and is the component used in this blend.
What is Ipamorelin?
Ipamorelin is a synthetic pentapeptide characterized as a selective agonist at the growth-hormone secretagogue receptor (GHS-R1a). Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.
What is Ipamorelin studied for in research?
It is used as a reference agonist in GHS-R1a receptor-binding and secretagogue-pathway signaling research in in-vitro and pre-clinical models. Verve makes no claims about effects in humans or animals.
related comparisons
verve products are sold for laboratory research and development purposes only and are not intended for human or veterinary use of any kind. statements on this site have not been evaluated by the FDA.